The father of a girl who went missing from her home in Childers, in southern Queensland, believes her abductor knew the family.

The father of missing three-year-old Chloe Campbell believes someone who knows the family took her.

Garth Campbell says there is no way his youngest daughter could have left their family home alone.

When he awoke on Thursday morning, Chloe, who usually sleeps in the lounge, was missing.

A window was open and when he looked out, an adult-sized footprint was on the car.

Chloe’s sleeping bag – patterned with wizards and dragons – was gone as well as her trusty companion, a stuffed toy dog named Gnarly.

“I don’t think there’s any possible way she’s wandered off,” Mr Campbell told AAP.

“She wouldn’t leave the yard by herself.”

The family usually shuts the windows of their Childers’ home at dusk each night to keep out mosquitoes, but on Wednesday Mr Campbell believes one of the latches must not have caught.

“That’s why we are blaming ourselves,” he said.

Chloe’s two older sisters Janae, eight, and Britney, five, have their own room in the two-bedroom Childers house.

But on Wednesday all three girls slept in the lounge.

When Janae awoke to go to the toilet in the morning, Chloe wasn’t in the lounge room, Mr Campbell said.

Janae had thought Chloe had sneaked into her parent’s room as she had been sick lately.

A distraught Mr Campbell believes that someone who knew where Chloe slept took her.

“I think it’s got to be someone who knows me, in how they got in, where she sleeps,” Mr Campbell said.

“They knew she was sleeping in front of the TV.”

Mr Campbell is asking for prayers and is clinging to hope that if Chloe’s been abducted, she is being cared for.

“I hope someone that’s taken her is looking after her,” he said.

“Giving her brekky, lunch, I don’t know, I don’t know what to think.

“Maybe someone took her who can’t have kids or something like that.”

Mother Tammy Campbell reported Chloe missing at 7am Thursday.

A major land and air search is underway and will go into the night.

Police tape has been placed around the house and the nearby showground is being searched.

“We hold very serious concerns for the safety for the little girl, as we do for every missing person reported,” Inspector Kevin Gutteridge said.

Childers, about a half hour drive southwest of Bundaberg, has a population of less than 1500.