A man is in hospital with head injuries and internal bleeding after being struck by an unknown vehicle during a hit and run accident in southern Brisbane.

A man has head injuries and internal bleeding after a hit and run accident in southern Brisbane.

The 56-year-old man is believed to have been struck by a vehicle on Logan Rd, Holland Park, on Friday night.

Police say the unknown vehicle then drove off, leaving the man on the road, about 10.45pm (AEST).

He had serious head injuries and internal bleeding and was rushed to hospital.

Investigators are urging anyone who may have witnessed the incident or who has any information which could assist with their inquiries to call Crime Stoppers on 1800 333 000.