The fate of accused wife killer Gerard Baden-Clay is now in the hands of a Brisbane jury, which has retired to consider its verdict.

Jurors in the murder trial of former Brisbane real estate agent Gerard Baden-Clay have retired to consider their verdict.

Supreme Court Justice John Byrne ended his summary of the 18-day trial on Thursday morning.

The seven men and five women on the jury retired to begin deliberations at 11.10am (AEST).

Baden-Clay, 43, has pleaded not guilty to murdering his wife Allison in April 2012.

Her body was found on a creek bank at Anstead in Brisbane’s west on April 30, 2012, ten days after her husband reported her missing from their home in nearby Brookfield.

During the trial prosecutors said the father of three probably smothered his wife at their house and dumped her body where it was found under the Kholo Creek Bridge.

Baden-Clay has vehemently denied killing his wife and his defence team said she could have taken her own life or died accidentally after wandering off at night.

The trial heard from 75 witnesses, including Baden-Clay’s former mistress Toni McHugh and Queensland MP Bruce Flegg, who knew Baden-Clay and lived near him.

Allison’s parents Geoff and Priscilla Dickie also gave evidence, while recorded police interviews with the couple’s three children were played in court.

Details of Baden-Clay’s multiple affairs, his financial woes and Allison’s history of depression were laid bare during more than four weeks of proceedings.

About 180 items were submitted as evidence, including photographs of scratches on Baden-Clay’s face and photographs of a trickle of Allison’s blood found in the couple’s car.